Scientist / Senior Scientist, Molecular Biology

Carcell, Singapore


Carcell is an EVX company that is building an “assembly line” business model that empowers rapid cell and gene therapy development. Co-founded by biotech veterans and backed by elite VCs, Carcell’s core capabilities cover all essential aspects of drug development including pre-clinical R&D, IP licensing and management, CMC and manufacturing, IND filing and clinical testing. This core platform will support multiple cell and gene therapy programs, with an initial focus on immune-oncology, autoimmune diseases and rare diseases. We believe that Carcell’s model of a centralized cell and gene therapy platform will rapidly and cost-efficiently translate innovative research into successful clinical products.

Carcell has R&D teams, central function teams, and manufacturing infrastructure based in Shanghai, Singapore, and Boston (upcoming).

We are looking for a Scientist / Senior Scientist with molecular biology background and expertise to join our R&D team in Singapore in this exciting venture. An ideal candidate is one who is technically competent, an effective communicator, and able to manage a team efficiently across multiple projects. This role reports to the Head of Molecular Biology.


  • Perform independent research work through the design, execution and troubleshooting of experiments

  • Interface with and manage external collaborators, including CROs, clinical and academic laboratories

  • Analyze, interpret and report experimental results to the research group and other key stakeholders

  • Provide scientific expertise, stay up to date on the latest relevant scientific literature, and mentor others in research findings and techniques.

  • Contribute to scientific and strategy discussions to achieve R&D milestones

  • Maintain accurate and detailed documentation of research data, inventories, protocols, maintenance logs, sample processing logs, SOPs etc.

  • Support the continued protection, creation, and expansion of company’s intellectual property

  • Perform other related duties incidental to the work described herein


  • PhD in Molecular Biology, Biochemistry, Genetics, Synthetic Biology or a related discipline

  • 2-3 years of postdoctoral and/or industry experience is a plus

  • Extensive experience with nucleic acid chemistry, molecular cloning, genetic engineering/gene therapy, design of expression cassettes

  • Familiarity with the use of CRISPR/Cas9 gene editing, next-generation sequencing, LNPs, immunology (flow cytometry) will be an advantage

  • Experienced in general laboratory techniques that include mammalian cell transfection and handling, bacterial transformation, molecular assays (such as qPCR, ELISA, Western blot), nucleic acid extraction, purification and characterization (DNA & RNA)

  • Experienced in mouse work/in vivo animal models

  • Able to work in a fast-paced startup environment; Flexible, adaptable and adjusts quickly to changing strategic and tactical priorities

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